郝帅

郝帅                           

出生年月:1988年5月

最高学历学位:博士

职称:副教授

导师类型:硕导

联系方式:haoshuai@btbu.edu.cn

个人简历

教育经历:  

2010年毕业于北京理工大学,生命学院,获学士学位

2015年毕业于北京师范大学,生命科学学院,获博士学位

工作经历:

北京工商大学,沙巴官网开户,副教授  

主讲课程

本科生:《食品生物技术概论(双语)》,《食品安全与质量控制》,《食品风险监测与评估》,《食品安全检测技术进展

主要研究领域

食源性功能因子在肿瘤及营养性疾病中的干预作用及分子机制研究,食品功能性评价与开发,食品蛋白质与营养组学

主要学术成果(课题、论文、获奖、专利等)

承担的主要科研项目(限5项):

国家自然科学基金青年科学基金项目“基于动态蛋白质组学技术对藻蓝色素蛋白生物合成及组装机制的研究”,主持

北京市优秀人才培养资助项目“采用蛋白质组学技术对藻蓝色素蛋白合成调控的机制研究”,主持

参与国家重点研发计划课题“以健康为导向传统食品酿造工艺绿色升级及产业化应用”

发表的代表性论文(限10篇):

1. Hao Shuai, Li S, Wang J, et al. C-Phycocyanin suppresses the in vitro proliferation and migration of non-small-cell lung cancer cells through reduction of RIPK1-NF-κB cctivity, Marine Drugs, 2019, 17:1-17.

2. Hao Shuai, Li S, Wang J, et al. Phycocyanin exerts anti-proliferative effects through down-regulating TIRAP-NF-kB activity in human non-small cell lung cancer cells, Cells, 2019, 8:1-15.

3. Hao Shuai, Li S, Wang J, et al. Transcriptome analysis of phycocyanin-mediated inhibitory functions on non-small cell lung cancer A549 cell growth, Marine Drugs, 2018, 16:1-17.  

4. Hao Shuai, Li S, Wang J, et al. Phycocyanin reduces proliferation of melanoma cells through downregulating GRB2/ERK signaling, Journal of Agricutural and Food Chemistry, 2018, 66: 10921-10929.

5. Hao Shuai, Yan Y, Huang W, et al. C-Phycocyanin reduces inflammation by inhibiting NF-κB activity through downregulating PDCD5 in lipopolysaccharide-induced RAW 264.7 macrophages, Journal of Functional Foods, 2018, 42:21-29.

6. Hao Shuai, Yan Y, Li S, et al. The in vitro anti-tumor activity of phycocyanin against non-small cell lung cancer cells, Marine Drugs, 2018, 16,1-15.

7. Hao Shuai, Qin Y, Yin S, et al. Serum translationally controlled tumor protein is involved in rat liver regeneration after hepatectomy, Hepatology Research, 2016, 46:1392-1401.

8. Hao Shuai, Sun S, Xiao X, et al. Selective expression of transthyretin in subtypes of lung cancer, Journal of Molecular Histology, 2016, 47:239-247.

9. Hao Shuai, Luo C, Abukiwan A, et al. miR-137 inhibits proliferation of melanoma cells by targeting PAK2. Experimental Dermatology, 2015, 24: 947–952.

10. He J*, Hao Shuai*, Zhang H, et al. Chronological protein synthesis in regenerating rat liver, Electrophoresis, 2015, 36: 1622-1632.